Khaled Abdelrahman

Degrees / Credentials

BPharm (Alexandria University)
MSc (Alexandria University)
PhD (University of Calgary)

Titles

Assistant Professor, Department of Anesthesiology, Pharmacology & Therapeutics, Faculty of Medicine, UBC

Membership

Full Member

Dr. Khaled Abdelrahman holds BSc (Pharmaceutical Sciences) and MSc (Pharmacology) from Alexandria University. He received his PhD in 2015 from the University Calgary where he studied the molecular basis underlying altered cerebrovascular function in type 2 diabetes. He then joined the Departments of Cellular & Molecular Medicine and Neuroscience at the University of Ottawa to explore novel G protein-coupled receptor candidates that can be targeted pharmacologically to slow the progression of Alzheimer’s and Huntington’s diseases. His research was supported by prestigious salary awards offered by Canadian Institutes for Health Research and Alberta Innovates. He is also the recipient of the Canadian Society of Pharmacology and Therapeutics Postdoctoral award and many young investigator awards from the American Society for Pharmacology and Experimental Therapeutics. He is a Registered Pharmacist with over 12 years of clinical expertise in providing patient care. He is currently an Assistant Professor in the Department of Anesthesiology, Pharmacology and Therapeutics in the Faculty of Medicine at the University of British Columbia.

Contact Info

Phone
604-822-1390
Mailing Address
212 - 2176 Health Sciences Mall
Vancouver, BC V6T 1Z3

Research Information

Dr. Khaled Abdelrahman’s lab focuses on exploring the contribution of some G protein-coupled receptors (GPCRs) to the impaired neurovascular coupling and cerebral blood flow autoregulation in Alzheimer’s disease mouse models. His lab employs in vitro, ex vivo and in vivo approaches to identify novel GPCR candidates that can be targeted pharmacologically to correct neurovascular coupling and slow neurodegeneration. His lab is also interested in studying what aspects of GPCR signaling are regulated in a sex-selective manner and how this can influence drug discovery in the area of neurodegenerative diseases.

Publications

Keywords

  • Alzheimer's disease
  • GPCRs
  • Glutamate
  • neurovascular coupling
  • cerebral blood flow
  • neuropharmacology
  • neuroglia