Development of a whole-brain memory trace pipeline for activity-dependent tagging murine lines
Rudy North Lecture Theatre, Djavad Mowafaghian Centre for Brain Health 2215 Wesbrook Mall, VancouverWe previously created a mouse model to permanently label neurons activated during learning, the ArcCreERT2 mice (Denny et al., 2014, Neuron). In our first publication, we extensively characterized the ArcCreERT2 mice and manipulated various parameters to correlate behavioral expression with memory tagging. Using contextual fear conditioning (CFC), we showed that mice re-exposed to a fearful […]
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