Zoom option if unable to attend in person
Over the past 25 years the costs of drug development have been rising steeply, with later phases being particularly resource intensive. Molecular imaging (primarily PET) has become an indispensable tool in early phase drug development, especially for compounds focused on CNS targets, PET studies conducted at an appropriate enable the refinement of the dose range to be explored in later phase studies, leading to time and resource savings, as well as providing early demonstration of compounds that are going to fail, leading to early termination and the reallocation of considerable resources. This talk will discuss the application of PET and MR imaging in early phase drug development, within the framework of the “three pillars” of drug development and provide examples of such studies.