Speaker: Dr. Oscar Marin, Kings College London
Title: Maturation and plasticity of cortical interneurons
GABAergic interneurons play crucial roles in regulating neuronal activity in the cerebral cortex. A hallmark of cortical interneurons is their remarkable structural and functional diversity, yet the molecular determinants and the precise timing underlying their diversification remain largely unknown. The search for mechanisms controlling the diversity of GABAergic interneurons has primarily focused on transcriptional programs driving the initial specification of different types of interneurons. However, relatively little is known about the mechanisms regulating their terminal differentiation. In this talk, I will describe molecular mechanisms controlling the maturation and plasticity of PV+ interneurons, a subclass of cortical interneurons that is particularly vulnerable across a broad spectrum of psychiatric disorders.
Speaker: Dr. Beatriz Rico, Kings College London
Title: TBD