Events

Microglia are the primary immune cell of the brain, but have roles outside of immunity as well as being implicated in the pathogenesis of many CNS disorders. Here I will show how we can use CSF1R inhibitors to control the microglial population in vivo, and elucidate their functions in both the homeostatic and disease brains. […]

Zoom option if unable to attend in person Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 Over the past 25 years the costs of drug development have been rising steeply, with later phases being particularly resource intensive. Molecular imaging (primarily PET) has become an indispensable tool in early phase drug development, […]

For decades, neuroscience has focused almost exclusively on stereotyped, reductionist, and over-trained behaviors due to their ease of study. In contrast, naturalistic behavior provides a rich diversity of movements, but this feature also largely precludes it from quantification and use. Recent advances in computer vision have enabled automatic tracking of the position of body parts - but position […]

Zoom option if unable to attend in person Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 The CNS is an immune-privileged organ, yet we know that peripheral immunity is critical for proper brain function. Here we will discuss cell communications in the meninges that regulate patrolling T cells and how the […]

Zoom option if unable to attend in person Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 The study of how the brain regulates learned fear has been fundamental to understanding brain function and has served as a pre-clinical animal model for fear- and anxiety-related disorders in humans. The current model has […]

Maternal cannabis use is a growing public health concern, yet the long-term effects of prenatal cannabis exposure remain elusive. Our understanding of how prenatal cannabis exposure affects the brain and behavior is critically informed by preclinical animal models that capture core components of human cannabis use. To this end, our laboratory and others have recently […]

Professor George Augustine –  Nanyang Technological University, Singapore Talk Title: "Synapses and synaptic circuits in health and disease" Professor Lim Kah Leong – Nanyang Technological University, Singapore Talk Title: "Neuroprotective and neurorestorative strategies for Parkinson’s disease" Professor Nagaendran Kandiah –  Nanyang Technological University, Singapore Talk Title: "Fluid biomarker and neuroimaging profile of mild cognitive impairment […]

Zoom option if unable to attend in person Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 Seeing is believing and thus, optical imaging techniques are extremely useful to study brain structure and function. I will present two projects aimed at providing the neuroscience community with better imaging instrumentation. In the first […]

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 99412 188589 Passcode: 188589 Dr. Michael Kobor is a Professor in the Department of Medical Genetics at the University of British Columbia (UBC) and The Edwin S.H. Leong UBC Chair in Healthy Aging—a UBC President’s Excellence Chair. He began […]

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Innate immunity plays a pivotal role in the pathophysiology of multiple sclerosis (MS) and important cell types involved in this process are CNS resident monocytes (microglia) and blood-derived macrophages. Chronic CNS inflammation in the MS […]

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Dr. Oka will discuss how innate instinct to consume water and salt is regulated through body-brain interactions.

Zoom option if unable to attend in person: Zoom link here (click on “Join a meeting”) Meeting ID: 91512 289258 Passcode: 289258 Objectives: 1) Neural stem cells build and regenerate the brain in part by forming oligodendrocytes, the myelinating cells of the central nervous system 2) Endogenous neural stem cells can be engaged in mouse models of neurodegenerative disorders for […]