Events

This event will be held virtually: Zoom link

Diseases of the brain are among the most challenging disorders to diagnose and treat. Unlike cancer, where human tissue biopsy specimens are routinely collected, brain disorders lack routine access to […]

The cerebellum has evolved to support basic sensory-motor functions. In the human brain, the cerebellar circuitry has dramatically expanded and contributes to virtually every cognitive function, including working memory, language, […]

Approach-avoidance (AA) conflict resolution is a form of decision making that is fundamentally important for survival and requires the effective evaluation of affective stimuli or events with mixed outcomes (positive […]

To make adaptive decisions we must cast ourselves into the future and consider the outcomes of our potential choices. This prospective consideration is informed by our memories. I will discuss […]

Speaking is a unique and defining human behavior.  Over the past decade, we have focused on deciphering the basic neural code that underlies our ability to speak fluently. During speech […]

Mild traumatic brain injury (mTBI) is the most common type of traumatic brain injury globally. Although its consequences may be short term, mTBI often leads to long-term neuropsychiatric and neurological […]

In 1973 John Heuser and Tom Reese demonstrated that neurotransmitter was released from neurons via the fusion of neurotransmitter-filled vesicles with the cell membrane.  But at the same time, these […]

Dopamine is a neuromodulator that codes information on various time scales. I will discuss recent progress on the identification of fast release mechanisms for dopamine in the mouse striatum. I will present data […]

Mammals use a sophisticated, multi-regional memory system to guide behavior. A major goal of neuroscience is to understand the mechanisms—ranging from molecular to cellular to systems—that make this possible. Spruston […]

The Heller Lab research program is focused on discovering molecular mechanisms by which epigenetic reprogramming contributes to neuropsychiatric disease. To this end, Dr. Heller pioneered the use of targeted epigenetic […]